In their latest research, the research team studied what precedes inflammation V the injury of hepatocytes caused by toxic chemicals, which sets in motion the inflammatory process? Their research showed that the absence of IKKfO in hepatocytes to increased c-Jun N – terminal kinase activation after exposure to a chemical carcinogen used to cause liver cancer in mice -. Importantly, deletion of the gene which prevents the major isoform of JNK in liver cells, the development of liver cancer, and conversely causes the tumor – enhancing effect by ablation of IKKfO.. A relationship between inflammation and cancer is known, the NF – kB pathway , which include the expression of genes regulated.
By the by the National Institutes of Health and the Superfund Basic Research Program. Karin is an American Cancer Society Research Professor. Continue reading